The Sickle IN Me
  • The
    • About Us >
      • To Donate
    • Our Mission >
      • BREAK THE STIGMA >
        • Believe IN We
    • Contact Us
  • Sickle
    • Sickle Activism
    • Sickle Education
    • Sickle Programming
  • In ME
    • Volunteer
  • Awareness
    • Awareness Ribbons
    • Events

Sickle News

This week in sickle cell news December 6th to the 13th 

12/13/2015

0 Comments

 
By Sean Marshall
It was announced this week by erurekalert.com as well as Boston medical and oakland medical that “treatment with the antiplatelet agent prasugrel does not significantly reduce the rate of pain crises or severe lung complications in children with sickle cell disease.” This information came to light by a report by the New England Journal of Medicine. This came as a shock because of the importance of the New England Journal is one of the largest and most geographically diverse international clinical trials on sickle cell disease to date.
This was proven by a “trial that was a double blind, randomized, placebo-controlled phase 3 clinical trial held at 51 sites across 13 nations in the Americas, Europe, the Middle East, Asia and Africa. Led by researchers at Dana-Farber/Boston Children's Cancer and Blood Disorders Center and UCSF Benioff Children's Hospital Oakland,”
This was all done because the clinic was attempting to actually reach a goal. That goal was “to create a trial the to determine whether prasugrel, a medication used in adult patients to reduce thrombotic cardiovascular events, could also significantly reduce the rate of rate of vaso-occlusive crises (VOCs) -- defined as pain crises or acute chest syndrome -- in children with sickle cell disease.”
Prasugrel is a drug that is suppose to “prevent platelets from aggregating by blocking an enzyme called P2Y12.” The good news is that the drug “is approved for use in adult cardiac patients in the U.S. to reduce the risk of clots following angioplasty or insertion of an arterial stent.”
This is a mixed bag. On the one hand it is disappointing that a drug that is suppose to be helping is not and there isn't an immediate solution, but it's always a good thing to know that certain medications are still being tested despite use by the public.
If there are any comments, questions, or ideas please contact us at thesickleinme@gmail.com
0 Comments



Leave a Reply.

    About 

    This section is solely to let our Sickle Soldiers tell their story trials & tribulations alongside things they feel are wrong in the Sickle Cell Community

    Archives

    March 2016
    February 2016
    January 2016
    December 2015
    November 2015
    October 2015
    September 2015
    August 2015
    July 2015
    June 2015
    May 2015
    April 2015
    January 2015
    December 2014
    November 2014
    October 2014
    September 2014
    August 2014
    July 2014
    June 2014
    April 2014

    Categories

    All
    Anemia
    Cell
    Death
    District
    Life
    Music
    Rap
    Sad
    Setter
    Sickle
    Soldier
    Swag
    Trend
    Young

    RSS Feed

Powered by Create your own unique website with customizable templates.
  • The
    • About Us >
      • To Donate
    • Our Mission >
      • BREAK THE STIGMA >
        • Believe IN We
    • Contact Us
  • Sickle
    • Sickle Activism
    • Sickle Education
    • Sickle Programming
  • In ME
    • Volunteer
  • Awareness
    • Awareness Ribbons
    • Events